The Use of Carica papaya Extract Against Dengue
DOI:
https://doi.org/10.56570/jimgs.v2i1.82Keywords:
Dengue, Carica papaya extract, Papaya leaf, Papaya leaf juice, Anti-inflammatory, AnticancerAbstract
Dengue is a mosquito-borne infection and is considered a global pandemic in low-income countries. The papaya leaf extract of Carica papaya has therapeutic properties associated with increasing platelet count, inhibiting viral replication, decreasing inflammation, and anticancer aiding in the early recovery of patients. It is also easily accessible and inexpensive in Southeast Asia. No adverse events have been reported, and the medicinal nature of papaya leaf extract makes it an advantageous tool against the Dengue pandemic.References
Harapan H, Michie A, Sasmono RT, Imrie A. Dengue: A Minireview. Viruses. 2020;12(8):829. doi:10.3390/v12080829
Chen R, Vasilakis N. Dengue — Quo tu et quo vadis? Viruses. 2011;3(9):1562-1608. doi:10.3390/v3091562
Singh SP, Kumar S, Mathan SV, et al. Therapeutic application of Carica papaya leaf extract in the management of human diseases. DARU J Pharm Sci. 2020;28(2):735-744. doi:10.1007/s40199-020-00348-7
Bere AW, Mulati O, Kimotho J, Ng’ong’a F. Carica papaya Leaf Extract Silver Synthesized Nanoparticles Inhibit Dengue Type 2 Viral Replication In Vitro. Pharmaceuticals. 2021;14(8):718. doi:10.3390/ph14080718
Rajapakse S, de Silva NL, Weeratunga P, Rodrigo C, Sigera C, Fernando SD. Carica papaya extract in dengue: a systematic review and meta-analysis. BMC Complement Altern Med. 2019;19(1):265. doi:10.1186/s12906-019-2678-2
Wang MW, Hao X, Chen K. Biological screening of natural products and drug innovation in China. Philos Trans R Soc B Biol Sci. 2007;362(1482):1093-1105. doi:10.1098/rstb.2007.2036
Teh BP, Ahmad NB, Mohamad SB, et al. Carica papaya Leaf Juice for Dengue: A Scoping Review. Nutrients. 2022;14(8):1584. doi:10.3390/nu14081584
Hettige S, Pushpakumara J, Wanigabadu LU, et al. Controlled clinical trial on effect of ‘Carica papaya’ leaf extract on patients with dengue fever. J Clin Res Med. 2020;3(3):1-7.