Journal For International Medical Graduates <article class="text"> <h1><u>OUR AIM</u></h1> <p>If we define our aim in one word, it’s “Service”. Our mission and aim is to serve science, scientific community, students, doctors, patients, &amp; readers by providing correct and accurate scientific evidence-based information. Our goal is to be recognized as the journal that serves people and supports merit and publishes high quality articles with correct and accurate scientific information.<br /><br />We also aim to serve science by providing maximum visibility of articles published in the journal by making them available to all the readers.<br /><br />The JIMG also serves the authors by providing fast speed publication in 30 to 60 days while maintaining diligent peer review process. All articles are submitted online, and peer review is conducted electronically to operate a transparent peer review system for the authors to increase transparency. The reviewer's reports are provided to the authors before publishing.<br /><br />Another aim of JIMG is to provide economical online publication platform for IMGs where many journals charge a handsome fee of thousands of dollars, JIMG publishing fee is nominal under 250 USD to 300 USD per article. We give IMGs the opportunity to not only publish their articles but also join our team of reviewers and editorial board members.<br /><br />JIMG also serves the reviewers by paying reviewers for their service of reviewing articles. We are the first journal according to our knowledge that pays reviewers per article fee for reviewing the article. In a nutshell, JIMG serves all parties involved in the process of writing and publishing.</p> </article> <p><br /><br /></p> <article class="text"> <h1><u>SCOPE</u></h1> <p>The journal targets medical students, doctors, clinicians of all fields, patients, research scientists, and readers worldwide. We equip international medical personnel with the necessary knowledge at the comfort of their homes.<br /><br />JIMG publishes original articles (clinical trials, and observational studies), review articles (traditional reviews, scoping reviews, mapping reviews, systematic reviews, and meta-analysis), letters to the editor, opinion articles, idea article, editorial articles, animal studies, in-vitro studies and all kinds of empirical studies on a broad range of medical topics, including endocrinology, dermatology, cardiology, gastroenterology, nephrology, hematology, hematology, rheumatology, immunology, microbiology, pathology, pediatrics, gynecology and obstetrics, anesthesiology, ophthalmology, psychiatry, general surgery, neurology, and oncology. In a nutshell, the journal is open to all fields related to medicine and healthcare.<br /><br />The journal is the official journal of California Institute Of Behavioral Neurosciences and Psychology and encourages CiBNP students and graduates to submit their articles to the journal. However, the journal is open for clinicians of all field across the globe. The articles whether submitted by the CiBNP students and graduates or non-CiBNP students will be processed on merit and will go through a proper peer-review process. If the reviewers consider the article unacceptable to be published by the JIMG, the article will be rejected. No personal likes and dislikes will be considered while making the decision of publication. The JIMG will follow the journal policies and operations guidelines to decide the fate of the article which is strictly merit based.<br /><br />For any queries and concerns please contact<br /><br />In a nutshell, JIMG serves all parties involved in the process of writing and publishing.</p> </article> en-US (Dr. Hassaan Tohid) (Dr. Hassaan Tohid) Tue, 30 Jan 2024 04:36:46 +0000 OJS 60 Role of Proprotein Convertase Subtilisin Kexin Type 9 Inhibitor Therapy in treatment of Patients with Polycystic Ovary Syndrome: A systemic Review of Metabolic and Cardiovascular Outcomes <p>Polycystic Ovary Syndrome (PCOS) is a common endocrine condition that affects both obese and nonobese women of reproductive age group. Its clinical presentation is dysmenorrhea, hirsutism, acne, metabolic complications, infertility, and polycystic ovaries. The study is aimed to assess the efficacy of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors to lower dyslipidemia in women with PCOS to prevent long term cardio-metabolic complications. PCSK 9 Inhibitors ( Alirocumab, Evolocumab, and Inclisiran) bind to LDL receptors in liver and lower LDLC levels, preventing long term adverse side effects. This review aims at showing that these drugs can be effective when prescribed to women with PCOS earlyon to prevent some serious cardiovascular and metabolic complications in the long run. In terms of medical therapy, most physicians prescribe Metformin and Statins as first line agents to control risk factors. But much of the research supported the use of PCSK 9 Inhibitors early in the disease process or as an add-on to statins for controlling the lipid profile. When compared to Statins, the control rates of PCSK 9 Inhibitors were equal or superior and they showed additive effect when given along with other lipid lowering agents. Studies showed these drugs have only minor side effects and have good tolerability profile. They do not have severe side effects as compared to statins or fibrates.</p> Dev Patel, Jabez John, Ranita Bodepudi, Saniya Seher, Shenel Khan, Soniya Emmanuel, Vivig Shantha, Resheek Nerella, Basim Shaman, Pousette Hamid Copyright (c) 2024 Journal For International Medical Graduates Mon, 19 Feb 2024 00:00:00 +0000 SENSITIZING INTERNATIONAL MEDICAL GRADUATES TO IDENTIFY NARCISSIST PERSONALIY DISORDER <p>Narcissistic personality disorder is a complex personality disorder that was first conceptualized by Sigmund Freud in 1914.Narcissistic personality disorder is characterized by a persistent sense of self-importance, grandiosity, and admiration of oneself.</p> Copyright (c) 2024 Journal For International Medical Graduates Mon, 20 May 2024 00:00:00 +0000 Impact of Pharmacogenomics Testing on Response to Antidepressants and Antipsychotics - A Systematic Review <p>With the sequencing of the human<br>genome and the subsequent revelation of the genetic<br>structures underlying many complex illnesses and<br>responses to many treatments, precision medicine has<br>emerged as a new player in the healthcare setting. We<br>aimed to assess the Impact of pharmacogenomics<br>testing on response to Antidepressants and<br>Antipsychotics</p> Sarah Alhaddad, Christian Paulsingh, Faisal Riaz, Gourav Garg, Lotanna Umeano, Sadaf Iftikhar, Tuheen Sanker Nath Copyright (c) 2024 Journal For International Medical Graduates Thu, 18 Apr 2024 00:00:00 +0000 Comparing Endoscopy and Surgery: A Systematic Review of Early Colorectal Cancer Treatments <p>Colorectal cancer is a major type of gastrointestinal <br>cancer that significantly contributes to disease burden <br>and mortality, particularly among younger people. Early <br>colorectal cancer refers to the early stages of the <br>disease that require early detection and treatment to <br>improve the overall prognosis and survival. There are <br>various treatment options available for early colorectal <br>cancer, such as endoscopic resection, including methods <br>like transanal endoscopic microsurgery (TEMS), <br>endoscopic mucosal resection (EMR), or submucosal <br>dissection (ESD), as well as surgical resection, including <br>open and laparoscopic techniques. However, to make <br>informed decisions about which approach is best, it is <br>crucial to thoroughly understand the long-term <br>outcomes associated with each option. We <br>systematically reviewed the PubMed and Google Scholar <br>databases from 2013 to August 11, 2023, to obtain such <br>knowledge. We selected nine for in-depth analysis after <br>carefully reviewing 2761 articles, including those <br>written in English and focusing on human studies. The <br>review focused on individual benefits, merits, and <br>drawbacks, considering the extent of the disease, <br>clinical outcomes, survival, and complication rates. <br>Although endoscopic resection has the advantage of <br>being less invasive and promoting faster patient <br>recovery, it should be noted that its primary objective <br>may not necessarily be achieving complete excision <br>(R0). This is because there are potential obstacles, <br>including inadequate lymph node removal and <br>inaccurate T staging that may prevent the achievement <br>of R0. Nevertheless, it is important to stress that both <br>endoscopic and surgical resection ultimately share the <br>goal of complete excision and curing the patient. Finally, <br>this systematic review emphasizes the need for <br>additional research to fill knowledge gaps, improve <br>clinical decision-making, and promote the application of <br>sophisticated technology. As the landscape of early <br>colorectal cancer treatment evolves, a balanced <br>integration of endoscopic and surgical resection <br>procedures, together with emerging technologies, can <br>improve patient outcomes and increase treatment <br>efficacy.</p> Saisravika Kambham, Dhuha S. Al-Taie, Esraa M. AlEdani, Jahnavi Gurramkonda, Shaan Chaudhri, Amina Amin, Khushal Girigosavi, Indu Etta, Mohammed Omar Khan, Sanam Wasim Khan, Binay Kumar Panjiyar Copyright (c) 2024 Journal For International Medical Graduates Mon, 19 Feb 2024 00:00:00 +0000 CRITICAL CONSIOUSNESS FOR INTERNATIONAL MEDICAL GRADUATES <p>Critical consciousness is an intellectual framework that is promoted in<br>medical education. It helps to raise reflective awareness of professional<br>power in healthcare. Moral virtues such as politeness and honesty are<br>important to cultivate. The field of medicine plays a vital role in<br>improving the quality of life and enhancing the physical and intellectual<br>performance of human beings.</p> Dr. Humaira Shamim Copyright (c) 2024 Journal For International Medical Graduates Tue, 30 Jan 2024 00:00:00 +0000 Therapeutics Uses of Psychedelics in patients with psychiatric disorders A Systematic Review <p>The impact of psychedelic treatment on patients <br />suffering from psychiatric diseases like depression, <br />anxiety, post-traumatic psychiatric disorder (PTSD), <br />and existential distress related to cancer has become <br />very intriguing to psychiatrists in the modern era. <br />Serotonergic psychedelics include Lysergic acid <br />diethylamide (LSD), psilocybin, mescaline, ayahuasca, <br />and methylene-deoxy methamphetamine (MDMA) <br />which act agonistically on 5-hydroxytryptamine type 2-<br />A (5-HT2A) receptors. Psychedelics produce a wide <br />range of effects, based on varying sites of 5-HT2a <br />receptors, including changes in consciousness, <br />perception, mood, and behaviour. Psychedelics can lead <br />to both good and bad trips depending on the dose and <br />environment in which it is taken. We used systematic <br />approach by strictly following Preferred Reporting Items <br />for Systematic Reviews and Meta-analysis (PRISMA) <br />2020 guidelines. Data is extracted from pub med using <br />mesh strategy, and from google scholar and science <br />direct by using keywords. 10 review articles are selected <br />by using quality appraisal tools. The purpose of this <br />paper is to highlight the mechanism of action and role <br />of psychedelics in patients with mental health disorders. <br />In this review, we discussed the effective models of <br />neurodynamical changes produced by psychedelics, and <br />we also show that these substances can be used as a <br />potential treatment option for psychiatric patients. <br />Psychedelics have shown effective improvement in <br />psychiatric diseases in many pilot studies and <br />randomized controlled trials. There is still a debate <br />going on about which models best suggest their role in <br />the field of psychiatry.</p> Sarosh Nawaz, Abdulaziz Mohammed Althwanay, Esraa M. AlEdani MB Ch B, Harleen Kaur, Malik Kasapoglu, Rajesh Yadavalli, Ann Kashmer Yu Copyright (c) 2024 Journal For International Medical Graduates Thu, 18 Apr 2024 00:00:00 +0000 Accuracyof Ultrasound and CT scans in the Diagnosis of Acute Appendicitis in Children: A Systematic Review <p>Acute appendicitis (AA) is the most common surgical<br>emergency in childhood. Accurate and early diagnosis is<br>important because any delay in diagnosis may lead to<br>perforation or abscess formation. Today, abdominal<br>ultrasonography (US) and computed tomography (CT)<br>scans are the most common imaging methods used for<br>diagnosis. The aim of this study was to evaluate the<br>accuracy of US and CT scans in the diagnosis of AA in<br>children. We started our research by using online<br>libraries as our database. We searched PubMed, Google<br>Scholar, the Cochrane Library, and the Web of Science<br>for our data collection. We used both the medical<br>subject headings (MESH) and regular keywords. Our<br>review investigated English-language articles regarding<br>the accuracy of US and CT scans in the diagnosis of AA<br>in children (2013-2023) according to the Preferred<br>Reporting Items for Systematic Reviews and Meta Analyses (PRISMA) 2020 guidelines. Articles were<br>screened by title, abstract, inclusion and exclusion<br>criteria, and quality assessment tools. The search<br>identified 513 studies; eight were eligible for inclusion<br>in the analysis. A total of 3341 pediatric patients were<br>included across the eight observational studies in our<br>systematic reviews. The included articles revealed that<br>low-dose CT showed the highest accuracy in the<br>diagnosis of AA. Whereas the US showed the lowest.<br>However, the combination of US as the primary<br>examination followed by CT in a non-diagnostic US<br>yielded the highest sensitivity, specificity, and accuracy.<br>Also, some studies revealed that several factors<br>decreased the sensitivity of CT and US in diagnosing AA<br>in children, like different hospital settings, the<br>radiologist's experience, age, sex, body mass index,<br>and disease severity. According to the review articles, a<br>CT scan is the most accurate test and has high<br>sensitivity and specificity; however, the radiation<br>hazards are minimized using a CT scan as a primary tool<br>for diagnosis. US is easily accessible, cost-effective, and<br>has high sensitivity. However, it is operator-dependent,<br>has low specificity, and is incompatible with some young<br>children, so it can be used as a first-choice and low-dose<br>CT scan in complicated cases and non-diagnostic US.<br>Ideally, more</p> Chnoor Shirwan Hawrami, Erica Ricci, Kirubel Tesfaye Hailu, Korlos Salib, Sanath Savithri Nandeesha, Alousious Kasagga, Pousette Hamid Copyright (c) 2024 Journal For International Medical Graduates Thu, 18 Apr 2024 00:00:00 +0000