Can Targeted Interventions Aimed at Improving Mental Health and Reducing Symptoms of Depression in Hypertensive Patients, Lead to Increased Medication Compliance and Improved Longevity? A Systematic Review
DOI:
https://doi.org/10.56570/jimgs.v1i1.162Keywords:
Hypertension, medication compliance, depression, mental health, hypertensive patient, anxietyAbstract
Background: Hypertension is identified as a chronic disease leading to complications and untimely deaths if left untreated or undiagnosed. There are several factors that contribute to the worsening of hypertension either directly or indirectly. Medication noncompliance is one of the direct factors. Depression plays a significant role as an indirect factor which convolutes management goals in hypertension. Correlation of mental health and adherence to medication requires further exploration. Method: Medical databases such as PubMed, Cochrane library, Science direct were searched for relevant literature ranging between May 2013 and May 2023. The literature found was screened, checked for eligibility and 10 papers were reviewed. This was done using the Preferred Reporting Items for Systemic Review and Meta-analysis (PRISMA) guidelines. The finalized papers investigated the relationship between mental health/ depression and antihypertensive compliance. Improvement in mental health led to reduced blood pressure which was associated with better medication compliance. Result: The analysis encompassed 10 research papers involving a total of 12,121 patients, excluding 542 individuals who had concurrent chronic conditions. One of the studies had other chronic diseases in addition to hypertension in it. Among these papers, one included patient with additional morbidity alongside hypertension. The studies hailed from diverse locations including Nigeria, Palestine, China, and the USA, with a notable proportion of patients being of Chinese origin. This predominance of Chinese patients reflects the abundance of relevant studies conducted in China on the subject matter. Conclusion: The studies showed a significant improvement in blood pressure control with depression management. In the studies, other contributing factors to medication compliance were found and incorporated into this systematic review. Different methods were used to measure depression and medication compliance across the studies. All this warrant further research into the topic and how solutions can be implemented globally.References
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