journal

Journal For International Medical Graduates

California Institute of Behavioral Neurosciences and Psychology

US https://www.cibnp.com

2832-9864

172

Articles

Aspirin Versus Enoxaparin for Deep Vein Thrombosis Prevention After Orthopedic Surgery: A Review of Efficacy and Safety

Sayed A Mahmud

Mahmud

Sayed A

sau.mahmud@gmail.com

Anura Manandhar

Manandhar

Anura

anuramanandhar@gmail.com

Ghadeer Sabir

Sabir

Ghadeer

ghadeersabir@hotmail.com

Hala Abdeldady

Abdeldady

Hala

h.alaaeddin95@gmail.com

Adoum Oumar Abakar

Abakar

Adoum Oumar

adoum902@gmail.com

Ravindra Reddy Gangavarapu

Gangavarapu

Ravindra Reddy

qwertyreddy143@gmail.com

Iana Malasevskaia

Malasevskaia

Iana

iana.malasevscaia@gmail.com

California Institute of Behavioral Neurosciences and Psychology (United States)

https://ror.org/01ytd2n62

23 09 2024

Received: 2392024

2024

Journal For International Medical Graduates

Aspirin Enoxaparin LMWH Deep Vein Thrombosis DVT Venous Thromboembolism VTE Orthopedic Surgery

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Fingar KR, Stocks C, Weiss AJ, Steiner CA. Most Frequent Operating Room Procedures Performed in U.S. Hospitals, 2003–2012. In: Healthcare Cost and Utilization Project (HCUP) Statistical Briefs. Rockville (MD): Agency for Healthcare Research and Quality (US); December 2014.

American Association of Hip and Knee surgeons. 2023 Hip and Knee Implant Review: A publication and online information service on cost and quality issues in orthopedics [Internet] Available from: https://www.aahks.org/wp-content/uploads/2023/10/onn343.pdf Accessed [June 30 2024]

marks julie. Blood Clots After Surgery [Internet]. WebMD. 2022. Available from: https://www.webmd.com/dvt/blood-clots-after-surgery Accessed [June 30 2024]

Blood Clots. Blood Clots in Orthopedic Surgery Fact Sheet [Internet]. Available from: https://www.stoptheclot.org/about-clots/toolkit-for-knee-hip-replacement-patients/orthopedic-surgery-fact-sheet/#:~:text=DVT%20is%20widely%20recognized %20as. Accessed [June 30 2024]

Akpinar EE, Hoşgün D, Akan B, Ateş C, Gülhan M. Does thromboprophylaxis prevent venous thromboembolism after major orthopedic surgery?. J Bras Pneumol. 2013;39(3):280-286. doi:10.1590/S1806-37132013000300004.x

Piovella F, Wang CJ, Lu H, et al. Deep-vein thrombosis rates after major orthopedic surgery in Asia. An epidemiological study based on postoperative screening with centrally adjudicated bilateral venography. J Thromb Haemost. 2005;3(12):2664-2670. doi:10.1111/j.1538-7836.2005.01621

Lee SY, Ro du H, Chung CY, et al. Incidence of deep vein thrombosis after major lower limb orthopedic surgery: analysis of a nationwide claim registry. Yonsei Med J. 2015;56(1):139-145. doi:10.3349/ymj.2015.56.1.139

MeSH | Cochrane Library [Internet]. www.cochranelibrary.com. Available from: https://www.cochranelibrary.com/advanced-search/mesh

Núñez JH, Moreira F, Escudero-Cisneros B, et al. Risk of venous thromboembolism in thromboprophylaxis between aspirin and low molecular weight heparins after total hip arthroplasty or total knee arthroplasty: Systematic review and meta-analysis. Riesgo de tromboembolismo venoso en la tromboprofilaxis entre aspirina y heparinas de bajo peso molecular tras una artroplastia total de cadera o artroplastia total de rodilla. Revisión sistemática y metaanálisis. Rev Esp Cir Ortop Traumatol. 2024;68(4):409-421. doi:10.1016/j.recot.2023.07.003.

Haac BE, O'Hara NN, Manson TT, et al. Aspirin versus low-molecular-weight heparin for venous thromboembolism prophylaxis in orthopaedic trauma patients: A patient-centered randomized controlled trial. PLoS One. 2020;15(8):e0235628. Published 2020 Aug 3. doi:10.1371/journal.pone.0235628.

Major Extremity Trauma Research Consortium (METRC), O'Toole RV, Stein DM, et al. Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture. N Engl J Med. 2023;388(3):203-213. doi:10.1056/NEJMoa2205973.

Pretorius J, Nemat N, Azeem I, Shaju T, Nadeem S, Hammad Y. Is aspirin still relevant as a single pharmacological agent for venous thromboembolism prophylaxis post hip and knee arthroplasty surgery: A retrospective review. SICOT J. 2022;8:28. doi:10.1051/sicotj/2022029.

CRISTAL Study Group. Aspirin or enoxaparin for VTE prophylaxis after primary partial, total or revision hip or knee arthroplasty: A secondary analysis from the CRISTAL cluster randomized trial. PLoS One. 2024;19(4):e0298152. Published 2024 Apr 16. doi:10.1371/journal.pone.0298152.

Zou Y, Tian S, Wang Y, Sun K. Administering aspirin, rivaroxaban and low-molecular-weight heparin to prevent deep venous thrombosis after total knee arthroplasty. Blood Coagul Fibrinolysis. 2014;25(7):660-664. doi:10.1097/MBC.0000000000000121.

Cortes-De la Fuente AA, Villalobos-Campuzano C, Bucio-Paticio B, Valencia-Martínez G, Martínez-Montiel O. Estudio comparativo entre enoxaparina y ácido acetilsalicílico en profilaxis antitrombótica para pacientes sometidos a artroplastía total de rodilla [Comparative study between enoxaparin and salicylic acetyl acid in antithrombotic prophylaxis for patients undergoing total knee arthroplasty]. Acta Ortop Mex. 2021;35(2):163-168..

Meng J, Liu W, Xiao Y, Tang H, Wu Y, Gao S. The role of aspirin versus low-molecular-weight heparin for venous thromboembolism prophylaxis after total knee arthroplasty: a meta-analysis of randomized controlled trials. Int J Surg. 2023;109(11):3648-3655. Published 2023 Nov 1. doi:10.1097/JS9.0000000000000656.

Singjie LC, Halomoan R, Saleh I, Sumargono E, Kholinne E. Clinical effectiveness and safety of aspirin and other anticoagulants for venous thromboembolism prophylaxis after major orthopedic surgery: a systematic review and meta-analysis of randomized clinical trials. EFORT Open Rev. 2022;7(12):792-799. Published 2022 Dec 21. doi:10.1530/EOR-22-0053.

Farey JE, An VVG, Sidhu V, Karunaratne S, Harris IA. Aspirin versus enoxaparin for the initial prevention of venous thromboembolism following elective arthroplasty of the hip or knee: A systematic review and meta-analysis. Orthop Traumatol Surg Res. 2021;107(1):102606. doi:10.1016/j.otsr.2020.04.002.

Wei Q, Sun J, Bai Y, et al. Aspirin versus LMWH for VTE prophylaxis after orthopedic surgery. Open Med (Wars). 2023;18(1):20230760. Published 2023 Aug 26. doi:10.1515/med-2023-0760